STATISTICS APPLIED TO CLINICAL TRIALS 4E
Ton J. Cleophas，Aeilko H. Zwinderman，Toine F. Cleophas，Eugene P. Cleophas
In the past few years many important novel methods have been applied in published clinical research. This has made the book again rather incomplete after its previous edition. The current edition consists of 16 new chapters, and updates of the 31 chapters from the previous edition. Important methods like Laplace transformations, log likelihood ratio statistics, Monte Carlo methods, and trend testing have been included. Also novel methods like superiority testing, pseudo-R2 statistics, optimism corrected c-statistic, I-statistics, and diagnostic meta-analyses have been addressed.